Today’s video goes through a genetic and biochemical analysis of SARS-CoV-2
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Slide 1: • Full sequence for Bat-CoV RaTG13 was not known (not in database) prior to the pandemic. The group that isolated Bat-CoV RaTG13 had originally sequenced just the polymerase. Upon a hit with the SARS-CoV-2 polymerase, the group retrieved the frozen isolate (which had remained cryopreserved ever since) to sequence the whole genome. It was at this point the 96% homology was elucidated. • Link to A pneumonia outbreak associated with a new coronavirus of probable bat origin paper in Nature https://www.nature.com/articles/s41586-020-2012-7 • The above image is from the Netflix original Coronavirus, Explained S1:E1. Slide 2, 3 and 4: • Link to The proximal origin of SARS-CoV-2 paper in Nature Medicine https://www.nature.com/articles/s41591-020-0820-9
Hi! My three years of study in Microbiology and Immunology at McGill University have fostered my interests in infectious diseases, vaccinology and scientific communication. McGill’s TEAM and TEACH awards have given me the privilege to enhance the quality of education in a variety of biomedical courses, spanning topics in molecular mechanisms of cell function, metabolic biochemistry, microbial physiology and fundamental virology. I aspire to be an infectious disease physician, and have a passion for philosophy as it arises in clinical practice (namely biomedical ethics). My favourite antibody is IgA2 for its underappreciated role in mucosal immunity, my favourite immunological concept is trained immunity for the role of memory in the innate response, and I don’t know what I would do without soccer in my life!
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