research re-hashed

The latest nCov-19 research, de-mystified


We’ve started to recruit scientific experts to review our posts! Any post that has been fully reviewed by a scientific expert (usually a university professor) will be labelled as ‘reviewed’ at the start of the post.


Investigating T cell Immune Response to SARS-CoV-2

This post was reviewed by Dr. Emily Bowman, one of our subject matter experts. The paper we’re demystifying today can be found here, if you’d like to tag along! Summary Researchers investigated the immune system’s T-cell response to the SARS-CoV-2 virus in people who were completely unexposed to COVID-19, people who were exposed to COVID-19 … Continue reading Investigating T cell Immune Response to SARS-CoV-2

The In-Crowd: SARS-CoV-2 vs. Your Microbiome

Image credit: “Petri dishes with cultures of bacteria grown on agar jelly.” by M. J. Richardson is under a CC BY-SA 2.0 License. This post was reviewed by Dr. Brett Finlay, one of our subject matter experts. This study was conducted by researchers from The Chinese University of Hong Kong. The paper we’ll be demystifying … Continue reading The In-Crowd: SARS-CoV-2 vs. Your Microbiome

Effect of SARS-CoV-2 infection in human airway cells

This post was reviewed by Dr. Jasmin Chahal, one of our subject matter experts. For the original article, please follow this link. TL;DR:  Compared to other coronaviruses (SARS-CoV and HCoV-NL63), SARS-CoV-2 spreads much more efficiently in a short time although all three coronaviruses use the same receptor to enter the cell and infect it. In … Continue reading Effect of SARS-CoV-2 infection in human airway cells

A Peek at Pfizer’s Vaccine Candidate

This post was reviewed by Dr. Zachary Benet, one of our subject matter experts. The paper we’re demystifying today can be found here, if you’d like to follow along. TL;DR BNT162b1 is an RNA-based vaccine against SARS-CoV-2. This Phase 1/2 clinical data is promising, because it shows that vaccination causes a strong antibody response, including neutralizing … Continue reading A Peek at Pfizer’s Vaccine Candidate

UV Rays Zap Human Coronaviruses

Image credit: “Fluorescent Led Ultraviolet” by sum+it is under the Pexels License This post was reviewed by E. Idil Temel, one of our subject matter experts. This study was conducted by researchers from Columbia University Irving Medical Center. The paper we’ll be demystifying can be found here, if you’d like to follow along! TL;DR: Researchers investigated … Continue reading UV Rays Zap Human Coronaviruses

The Oxford Saga: A New Hope

This post has been reviewed by Dr. Brett Finlay and Dr. Carolina Camargo, some of our subject matter experts. The paper we’re demystifying today can be found here, if you’d like to follow along. TL;DR: The Gilbert group’s vaccine candidate, ChAdOx1 nCov-19, was found to be safe and well-tolerated in the group of patients that … Continue reading The Oxford Saga: A New Hope

Potential COVID-19 Drug Target: 3CL Mpro

For the original article, please follow this link. This post was reviewed by Dr. Kelly Summers and Dr. Andrey Kovalevsky, some of our subject matter experts. Brief Summary 3CL Mpro is a SARS-CoV-2 enzyme (the virus causing COVID-19) that processes other SARS-CoV-2 polyproteins (by slicing them up into smaller pieces) critical for the viral life cycle … Continue reading Potential COVID-19 Drug Target: 3CL Mpro

Gone with the Wind: SARS-CoV-2 in the Air

This post was reviewed by Dr. Zachary Benet, one of our subject matter experts. The paper we’ll be demystifying can be found here, if you’d like to follow along! This research was conducted by scientists at Erasmus University Medical Center in The Netherlands. TL;DR: Researchers infected ferrets with SARS-CoV-2 and placed these ‘patient zero’ ferrets … Continue reading Gone with the Wind: SARS-CoV-2 in the Air

Monkeying Around with a COVID-19 Vaccine

Image credit: “Gibraltar Barbary Macaque” by Redcoat is licensed under the Creative Commons Attribution-Share Alike 2.5 Generic license. This post was reviewed by Dr. Emily Bowman, one of our subject matter experts. This study was conducted by researchers from Beijing Bio-Institute Biological Products Co Ltd, China CDC, Peking Union Medical College, National Institute for Food … Continue reading Monkeying Around with a COVID-19 Vaccine

Does Physical Distancing and the Use of Face Masks and Eye Protection Prevent COVID-19 Transmission?

This article was reviewed by Idil Temel, one of our subject matter experts. The paper we’ll be demystifying can be found here, if you’d like to follow along! TL;DR Researchers in the present study found that 1-2m of physical distance can help decrease the spread of COVID-19. Furthermore, it was found that face masks and … Continue reading Does Physical Distancing and the Use of Face Masks and Eye Protection Prevent COVID-19 Transmission?

Up in Smoke with COVID-19

Image credit: “Person Smoking Cigarette” by fotografierende is under the Pexels License. This article was reviewed by Dr. Phil Lange, one of our subject matter experts. This study was conducted by researchers from Cold Spring Harbor Laboratory. The paper we’ll be demystifying can be found here, if you’d like to follow along! TL:DR; Researchers compared … Continue reading Up in Smoke with COVID-19

Babies Striking Back Against the Coronavirus

The paper we’re demystifying can be found here, if you’d like to follow along. This article was reviewed by Dr. Emily Bowman and Dr. Kelly Summers, two of our subject matter experts. Introducing New Diagnostic Criteria For COVID-19 Serologic tests are used to detect the body’s immune response to a viral infection by measuring the … Continue reading Babies Striking Back Against the Coronavirus

Cleaving the Basic Spike Protein

This post was reviewed by Dr. Sebastian Lequime, one of our subject matter experts. TL;DR: This group of researchers from Germany investigated the multibasic amino acid sequence in the S1/S2 cleavage site on the spike glycoprotein of SARS-CoV-2. They wanted to know how important this sequence is for cleavage and entry. They also found that … Continue reading Cleaving the Basic Spike Protein

What happened to all the ventilators?

This article was reviewed by Dr. Phil Lange, one of our subject matter experts. This research was conducted by scientists at the University of Washington, the Virginia Mason Medical Center, and the Swedish Medical Center (all in Seattle, WA). The paper we will be demystifying today can be found here, if you’d like to follow along. … Continue reading What happened to all the ventilators?

A DNA Vaccine for COVID19

This post was reviewed by Dr. Brett Finlay, one of our subject matter experts. The paper we’re demystifying today can be found here if you want to follow along. As you may know, the race for a vaccine against SARS-CoV-2, the virus that causes COVID-19, is on. According to one COVID19 vaccine tracker, there are at least 28 … Continue reading A DNA Vaccine for COVID19

Increased risk of blood vessel blockages in ICU patients with COVID-19

Patients with COVID-19 infections face a variety of risks, many of which are still being studied. COVID-19 may increase the risk of developing blood clots in both veins and arteries (venous & arterial thromboembolism). This prevents regions of the body from getting proper blood flow and this is dangerous if it affects a large area or vital organs such as the heart, lungs or brain.

COVID-19 Transmission: Is the Air Contaminated?

This post was reviewed by Dr. Carolina Camargo, one of our subject matter experts. For the original article, please follow this link. For the biological definitions of aerosols and respiratory droplets, please visit this page. Brief Summary This case study1 at two Wuhan Hospitals and public areas nearby detected the genetic material of SARS-CoV-2 in the air. … Continue reading COVID-19 Transmission: Is the Air Contaminated?

PAC-MAN vs. COVID-19

Image credit: “Pacman Games” by Piotr Siedlecki is under a CC0 Public Domain license. This study was conducted by researchers from Stanford University. This post was reviewed by Dr. Phil Lange, one of our subject matter experts. TL;DR: Stanford researchers investigated using PAC-MAN, a technique that destroys virus genes, to attack SARS-CoV-2. PAC-MAN was shown … Continue reading PAC-MAN vs. COVID-19

China Center for Disease Control: Fur Friends and SARS-CoV-2

This post was reviewed by Dr. Scott Covey, one of our subject matter experts. Summary of today’s paper: In this paper published in Science, scientists from the China Center for Disease Control and Prevention examine how well SARS-CoV-2 can transmit to and infect lab animal models, our companion pets, and farm animals. This is an … Continue reading China Center for Disease Control: Fur Friends and SARS-CoV-2

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