Cleaving the Basic Spike Protein

This post was reviewed by Dr. Sebastian Lequime, one of our subject matter experts. TL;DR: This group of researchers from Germany investigated the multibasic amino acid sequence in the S1/S2 cleavage site on the spike glycoprotein of SARS-CoV-2. They wanted to know how important this sequence is for cleavage and entry. They also found that … Continue reading Cleaving the Basic Spike Protein

Sidebar: How the different kinds of masks work

Over the last two months, many health experts around the world have begun to tell us that wearing a non-medical or surgical mask can provide work to decrease the number of respiratory droplets we may expel1,2. Facemasks, when used along with proper handwashing and social distancing, can protect from COVID-191. An important question to ask … Continue reading Sidebar: How the different kinds of masks work

China Center for Disease Control: Fur Friends and SARS-CoV-2

This post was reviewed by Dr. Scott Covey, one of our subject matter experts. Summary of today’s paper: In this paper published in Science, scientists from the China Center for Disease Control and Prevention examine how well SARS-CoV-2 can transmit to and infect lab animal models, our companion pets, and farm animals. This is an … Continue reading China Center for Disease Control: Fur Friends and SARS-CoV-2

Sidebar: I have plaques on my wall to commemorate the virus plaque assay

Welcome my fellow friends to a new short sidebar series! Over the next couple of weeks, I (Manolya Sag) Deanna Kim, and Jamie Lee will be going over some of the most common laboratory techniques many scientists are using to answer questions and make discoveries related to SARS-CoV-2. Many of the techniques we will be … Continue reading Sidebar: I have plaques on my wall to commemorate the virus plaque assay

The NAbs and DAbs Guide to Understanding How Antibodies Can Enhance Coronavirus Entry Into our Cells

This research was conducted at the University of Minnesota. This post was reviewed by Dr. Sebastian Lequime, one of our subject matter experts. (A little disclaimer, this paper and review does not talk about domain antibodies, but the opportunity to make a pun with NAbs and DAbs was right there, and I had to do it). … Continue reading The NAbs and DAbs Guide to Understanding How Antibodies Can Enhance Coronavirus Entry Into our Cells