Our author Demitri takes you through some of the key differences between SARS-CoV-2 and the common flu.
Author: Demitri Evangeliou
Hi! My three years of study in Microbiology and Immunology at McGill University have fostered my interests in infectious diseases, vaccinology and scientific communication. McGill’s TEAM and TEACH awards have given me the privilege to enhance the quality of education in a variety of biomedical courses, spanning topics in molecular mechanisms of cell function, metabolic biochemistry, microbial physiology and fundamental virology. I aspire to be an infectious disease physician, and have a passion for philosophy as it arises in clinical practice (namely biomedical ethics). My favourite antibody is IgA2 for its underappreciated role in mucosal immunity, my favourite immunological concept is trained immunity for the role of memory in the innate response, and I don’t know what I would do without soccer in my life!
Video Sidebar: SARS-CoV-2 VS Other Coronaviruses
https://videopress.com/v/aPlOtAr4?preloadContent=metadata References Link to Attenuation of replication by a 29 nucleotide deletion in SARS-coronavirus acquired during the early stages of human-to-human transmission paper in Nature Scientific Reports https://www.nature.com/articles/s41598-018-33487-8 Link to Report of the WHO-China Joint Mission on Coronavirus Disease 2019 (COVID-19) report https://www.who.int/docs/default-source/coronaviruse/who-china-joint-mission-on-covid-19-final-report.pdf Link to Preliminary estimation of the basic reproduction number of novel coronavirus … Continue reading Video Sidebar: SARS-CoV-2 VS Other Coronaviruses
Video Sidebar: Wrapping up- Where Did SARS-CoV-2 come from?
Before we launch into the video, we should first define the term "Divergent Evolution," which Demitri defines as: When at least 2 groups of the same species that originate from the same parent species independently acquire differences that are necessary for persistence in their respective environments. You can find out more about divergent evolution here. … Continue reading Video Sidebar: Wrapping up- Where Did SARS-CoV-2 come from?
Video Sidebar: Genetics of SARS-CoV-2
Today's video goes through a genetic and biochemical analysis of SARS-CoV-2 https://videopress.com/v/NabiKugx?preloadContent=metadata References: Slide 1:• Full sequence for Bat-CoV RaTG13 was not known (not in database) prior to the pandemic. The group that isolated Bat-CoV RaTG13 had originally sequenced just the polymerase. Upon a hit with the SARS-CoV-2 polymerase, the group retrieved the frozen isolate (which … Continue reading Video Sidebar: Genetics of SARS-CoV-2
Video Sidebar: SARS-CoV-2 Taxonomy and Origins
Today's video goes over basic coronavirus taxonomy and some of the details on SARS-CoV-2 origins https://videopress.com/v/BDAFEZMu?preloadContent=metadata Editor's notes: 3:10: Although the text at the bottom of the slide refers to D614G as a mutation, the better word for it would be an 'amino acid change.' The word mutation refers to a change in genetic code, … Continue reading Video Sidebar: SARS-CoV-2 Taxonomy and Origins