Our author Demitri takes you through some of the key differences between SARS-CoV-2 and the common flu.
https://videopress.com/v/aPlOtAr4?preloadContent=metadata References Link to Attenuation of replication by a 29 nucleotide deletion in SARS-coronavirus acquired during the early stages of human-to-human transmission paper in Nature Scientific Reports https://www.nature.com/articles/s41598-018-33487-8 Link to Report of the WHO-China Joint Mission on Coronavirus Disease 2019 (COVID-19) report https://www.who.int/docs/default-source/coronaviruse/who-china-joint-mission-on-covid-19-final-report.pdf Link to Preliminary estimation of the basic reproduction number of novel coronavirus … Continue reading Video Sidebar: SARS-CoV-2 VS Other Coronaviruses
Before we launch into the video, we should first define the term "Divergent Evolution," which Demitri defines as: When at least 2 groups of the same species that originate from the same parent species independently acquire differences that are necessary for persistence in their respective environments. You can find out more about divergent evolution here. … Continue reading Video Sidebar: Wrapping up- Where Did SARS-CoV-2 come from?
Today's video goes through a genetic and biochemical analysis of SARS-CoV-2 https://videopress.com/v/NabiKugx?preloadContent=metadata References: Slide 1:• Full sequence for Bat-CoV RaTG13 was not known (not in database) prior to the pandemic. The group that isolated Bat-CoV RaTG13 had originally sequenced just the polymerase. Upon a hit with the SARS-CoV-2 polymerase, the group retrieved the frozen isolate (which … Continue reading Video Sidebar: Genetics of SARS-CoV-2
Today's video goes over basic coronavirus taxonomy and some of the details on SARS-CoV-2 origins https://videopress.com/v/BDAFEZMu?preloadContent=metadata Editor's notes: 3:10: Although the text at the bottom of the slide refers to D614G as a mutation, the better word for it would be an 'amino acid change.' The word mutation refers to a change in genetic code, … Continue reading Video Sidebar: SARS-CoV-2 Taxonomy and Origins